Removing the Trial and Error from Medication Therapy

A PERSON IS BORN AN ORIGINAL

A PERSON'S MEDICATION THERAPY PLAN SHOULD BE JUST AS ORIGINAL

THE PROBLEM

TRIAL AND ERROR PRESCRIPTIONS

WHICH HAVE RESULTED IN MEDICATION ERRORS AND

LEFT INDIVIDUALS SICK AND FINANCIALLY DEVASTATED

THE SOLUTION

PHARMACOGENOMICS TESTING BASED MEDICATION THERAPY MANAGEMENT

Which Ensures a Person Receives the

CORRECT MEDICATION,

at the

CORRECT DOSE....

the FIRST TIME

and

EVERY TIME...

THUS ELIMINATING TRIAL AND ERROR PRESCRIPTIONS AND THEIR ASSOCIATED COSTS

What is Pharmacogenomics?

Pharm-a-co-ge-no-mics...

(sometimes called pharmacogenetics) is a field of research that studies how your genes affect how you respond to medications. Its long-term goal is to help your doctor, in collaboration with a specially trained inGENEious RX pharmacist, select the drugs and doses best suited for you. It is part of the field of precision medicine, which aims to treat you as the individual you are and as a result shorten your time to recovery and decrease your healthcare expenses.

YOUR GENES

determine a lot about how you look. They also play a key role in how medications work in your body.

What role do genes play in how medicines work?

Just as your genes determine your hair and eye color, they partly affect how your body responds to medicine.

Genes are instructions, written in DNA, for building protein molecules. Different people can have different versions of the same gene. Each version has a slightly different DNA sequence. Some of these variants are common, and some are rare. And some affect health, such as those gene variants linked to certain diseases.

CYP2D6

One liver enzyme, known as CYP2D6, acts on a quarter of all prescription drugs.

For example, it converts the painkiller codeine into its active form, morphine.

There are more than 160 versions of the CYP2D6 gene. Many vary by only a single difference in their DNA sequence. Others have larger changes. Most of these variants don’t affect how you respond to the drug.

Typically, people have two copies of each gene. However, some people have hundreds or even thousands of copies of the CYP2D6 gene. Those with extra copies produce too much of the CYP2D6 enzyme and process the drug very fast. As a result, their bodies may convert codeine to morphine so quickly and completely that a standard dose can be an overdose.

In contrast, some variants of CYP2D6 create an enzyme that doesn’t work. People with these variants process codeine slowly, if at all, leading to little, if any, pain relief. For them, inGENEious RX specially trained pharmacists can collaborate with prescribers to prescribe a different drug.

PROTEINS

Scientists know that certain proteins affect how drugs work.

Pharmacogenomics looks at variations in genes for these proteins.

Such proteins include liver enzymes that chemically change drugs. Sometimes chemical changes can make the drugs more—or less—active in the body. Even small differences in the genes for these liver enzymes can have a big impact on a drug’s safety or effectiveness.

FDA Oversight

The Food and Drug Administration (FDA) monitors drug safety in the United States.

CLICK HERE TO SEE IF A MEDICATION YOU ARE TAKING HAS FDA PHARMACOGENOMIC INFORMATION IN ITS LABELING

OUR PHARMACOGENOMICS CERTIFIED PHARMACISTS ARE AVAILABLE

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Saturday, 9AM -3PM EST
Sunday, closed

You don't work hard everyday just to pay medical bills

$3.5 billion is spent on excess medical costs of Adverse Drug Events annually

A nursing home is NOT the Place for YOU!

Older adults (65 years or older) are three times as likely as younger patients to come to emergency departments for adverse drug events

You don't' have time for the emergency room

Adverse drug events cause approximately 1.3 million emergency department visits each year

Protect YOUR Family

Approximately 200,000 children (17 years old or younger) visit emergency departments each year because of adverse drug events